Well, I've been trying SansGrip's Blockbuster a little more and have had amazing results with this setting: Blockbuster(method="dither",block_size=3,luma_offset=-2,luma_threshold=30,detail_min=1, detail_max=30) Although, I saw someone else post the block_size=3 and gave it a try, but I think it should divide evenly into the frame, no? On the encode I just tested of a TV cap of a cartoon, I had to look out for dark blocks watching through my TV, while normally they are so glaring it's unacceptable. Dither seems to be the key, as it stop the blocks from having a 'life of their own' (i.e. moving around or flickering where the image is relatively static). SansGrip mentions in the readme that dither is experimental so maybe this can still be improved. The place where I see blocks the most now is in somewhat bright solid colour areas. Instead of increasing the variables, I wonder if blockbuster can be modified to tackle a frame at both ends of the luma scale? Anyways try it out and report back your findings. Get his plugin